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PHYSIOLOGICAL
CONSIDERATIONS
Vital signs
Infants and children have a more rapid metabolic rate than
adults. This is reflected in their normal vital signs.

Temperature regulation
Children lose heat more rapidly than adults because they have
a greater relative surface area and are poorly insulated. Hypothermia
can affect drug metabolism, anaesthesia and blood coagulation.
Children are especially prone to hypothermia in the operating
room.
Prevent hypothermia by:
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Turning
off any air conditioning in the operating room (aim
for a room temperature of >28°C) |
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Using
warmed intravenous fluids |
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Avoiding
long procedures |
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Monitoring
the child’s temperature at least every 30 minutes
and at the completion of the case.
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It
is easier to keep children warm than to warm them up when
cold. Encourage the mother to keep the child warm.
Compensatory mechanisms for shock
Children compensate for shock differently from adults, mainly
by increasing their heart rate. A rapid heart rate in a child
may be a sign of impending circulatory collapse. Do not ignore
a decreased blood pressure. A slow heart rate in a child is
hypoxia until proven otherwise.
Blood volume
Children have smaller blood volumes than adults
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Even
small amounts of blood loss can be life threatening |
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Intravenous
fluid replacement is needed when blood loss exceeds
10% of the total blood volume |
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Chronic
anaemia should be slowly corrected before elective
operations with iron, folic acid or other supplements,
as appropriate |
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Make
sure that safe blood will be available in the operating
room if blood loss is anticipated during surgical
procedures.
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See The Clinical Use of Blood (WHO, 2000) for additional information
on the use of blood in paediatrics and neonatology.

Nutrition and hypoglycaemia
Infants and children are at special risk for nutritional problems
because of their higher caloric needs for growth. Poor nutrition
affects response to injury and ability to heal wounds. Many
surgical conditions, such as burns, increase caloric needs
or prevent adequate intake of needed nutrition.
Good nutrition helps healing. Poor nutrition prevents it.
Infants are at risk for developing hypoglycaemia because
of a limited ability to utilize fat and protein to synthesize
glucose. If prolonged periods of fasting are anticipated
(>6
hours), give intravenous fluids that contain glucose.
Fluid and electrolytes
Baseline fluid and electrolyte requirements are related to
the child’s weight. However, the actual fluid requirements
may vary markedly, depending on the surgical condition.
Hourly maintenance fluid requirements can be calculated using
the 4:2:1 rule.

Fluid requirements in surgical patients commonly exceed maintenance
requirements. Children with abdominal operations typically
require up to 50% more than baseline requirements and even
larger amounts if peritonitis is present. Special care is needed
with fluid therapy in children; pay close attention to ongoing
losses (e.g. nasogastric drainage) and monitor urine output.
In the case of fever, add 12% to total maintenance requirements
per 1°C rise above 37.5°C
temperature measured rectally.
The most sensitive indicator of fluid status in a child is urine output. If urinary
retention is suspected, pass a Foley catheter. A catheter also allows hourly
measurements of urine output that can prove invaluable in the severely ill patient.
Normal urine output: Infants 1–2 ml/kg/hour
Children 1 ml/kg/hour
Infants are unable to concentrate urine as well as adults, making them more susceptible
to electrolyte abnormalities.
Establishing intravenous access in paediatric patients can be challenging.
See pages 13–11 to 13–16 for IV access techniques.
Anaesthesia and pain control
Anaesthesia in children poses special problems. The smaller diameter airway
makes children especially susceptible to airway obstruction. Children often
need intubation to protect their airway during surgical procedures. Ketamine
anaesthesia is widely used for children in rural centres (see pages 14–14 to 14–21),
but is also good for pain control.
Children suffer from pain as much as adults, but may show it in different ways.
Make surgical procedures as painless as possible:
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Oral
paracetamol can be given several hours prior to operation |
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Local
anaesthetics (bupivacaine 0.25%, not to exceed 1 ml/kg)
administered in the operating room can decrease incisional
pain |
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Paracetamol
(10–15 mg/kg every 4–6 hours) administered
by mouth or rectally is a safe and effective method
for controlling postoperative pain |
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For
more severe pain, use intravenous narcotics (morphine
sulfate 0.05–0.1 mg/kg IV) every 2–4
hours |
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Ibuprofen
10 mg/kg can be administered by mouth every 6–8
hours |
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Codeine
suspension 0.5–1 mg/kg can be administered by
mouth every 6 hours, as needed.
Pre- and postoperative care |
The pre- and postoperative care of children with surgical problems is often as
important as the procedure itself. For this reason, surgical care of children
does not begin or end in the operating room. Good care requires teamwork, with
doctors, nurses and parents all having important roles to play:
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Prepare
the patient and family for the procedure |
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Ensure
that the needed paediatric supplies (such as intravenous
catheters, endotracheal tubes and Foley catheters)
are available in the operating room to complete the
procedure |
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Monitor
the patient’s vital signs during the critical
period of recovery |
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Encourage
a parent to stay with the child in the hospital and
to be involved in his/her care. |

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Infants and young children, especially
those with little subcutaneous fat, are unable to maintain
a normal body temperature when there are wide variations
in the ambient temperature or when they have been anaesthetized.
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Malnutrition can impair the response of children to injury
and their ability to heal and recover |
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When completing a preoperative assessment on a child,
consider nutritional status and anaemia; treat chronic
anaemia as part of the preparation for surgery.
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Whenever possible, give fluids by mouth
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Use the intravenous route for rapid resuscitation (20
ml/kg bolus of normal saline) and for cases where the oral
route is not available or inadequate
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Intraosseous puncture can provide the
quickest access to the circulation in a shocked child
in whom venous cannulation is impossible (see page 13–15).
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