| |
Peritonitis
is an acute life-threatening condition caused by bacterial
or chemical contamination of the peritoneal cavity. Neglected
chemical peritonitis will progress to bacterial peritonitis.
The treatment of peritonitis is the treatment of the underlying
cause.
Causes
The major causes of peritonitis include:
| :: |
Appendicitis |
| :: |
Perforated
peptic ulcer |
| :: |
Anastomotic
leak following surgery |
| :: |
Strangulated
bowel |
| :: |
Pancreatitis |
| :: |
Cholecystitis |
| :: |
Intra-abdominal
abscess |
| :: |
Haematogenous
spread of infective agents such as typhoid or tuberculosis |
| :: |
Typhoid
perforation |
| :: |
Ascending
infection: for example, in salpingitis and postpartum
infection. |
Clinical features
Clinical features of peritonitis include:
| :: |
Sharp
pain, which is worse on movement or coughing |
| :: |
Fever |
| :: |
Abdominal
distension, tenderness and guarding |
| :: |
Diminished
or absent bowel sounds |
| :: |
Shoulder
pain (referred from diaphragm) |
| :: |
Tenderness
on rectal or vaginal examination (suggests pelvic peritonitis). |
These features may be minimal in elderly patients, the very
young and those with immune suppression.
Management
| 1 |
Make
a differential diagnosis of the most likely underlying
cause of the peritonitis/abscess. |
| 2 |
Administer
normal saline or Ringer’s lactate, depending on
the serum electrolyte results. |
| 3 |
Insert
a nasogastric tube and commence aspirations. |
| 4 |
Give
triple antibiotic therapy intravenously, providing aerobic,
gram negative and anaerobic coverage. For example, ampicillin
2 g IV every 6 hours plus gentamicin 5 mg/kg body weight
IV every 24 hours plus metronidazole 500 mg IV every
8 hours. |
| 5 |
Record
fluid balance and vital signs on the bedside chart every
six hours. |
Surgical intervention will depend on the diagnosis of the cause
of the peritonitis: for example, appendectomy, closure of a
perforation or drainage of an abscess.
Intestinal obstruction may respond to non operative management,
but peritonitis indicates gangrene or perforation and therefore
requires surgery.

|
|
|